Patents & Publications

Zosano Pharma has a strong platform of both technology and product specific Intellectual Property. Zosano Pharma has secured 22 specific patent families. We continue to build our patent estate on a global basis.

Selected Publications

Human Growth Hormone Delivery with a Microneedle Transdermal System: Preclinical Formulation, Stability, Delivery and PK of Therapeutically Relevant Doses. 
M. Ameri, M. Kadkhodayan , J. Nguyen , J.A. Bravo , R.  Su , K. Chan,  A. Samiee, P.E. Daddona. Pharmaceutics. 2014, 6:220-34

Erythropoietin-Coated ZP-Microneedle Transdermal System: Preclinical Formulation, Stability, and Delivery
Elaine E. Peters & Mahmoud Ameri & Xiaomei Wang & Yuh-Fun Maa & Peter E. Daddona. Pharmaceutical Research 2012

Parathyroid Hormone (1-34)-Coated Microneedle Patch System: Clinical Pharmacokinetics and Pharmacodynamics for Treatment of Osteoporosis. 
Peter E Daddona, James A. Matriano, Jaap Mandema, Yuh-Fun Maa. Pharmaceutical Research 2010

Effect of transdermal teriparatide administration on bone mineral density in postmenopausal women. 
E. Lane, Michael A. Bolognese, Jose R. Zanchetta, Pedro A. Garcia-Hernandez, Karen Sees, James A. Matriano, Kim Gaumer, Peter E. Daddona. Journal of Clinical Endocrinolology & Metabolism. 95:151-58, 2010

Parathyroid Hormone PTH(1-34) Formulation that Enables Uniform Coating on a Novel Transdermal Microprojection Delivery System.
Mahmoud Ameri, Shelley C. Fan, Yuh-Fun Maa. Pharmaceutical Research 27, 303-313, 2010

Effect of irradiation on parathyroid hormone PTH(1-34) coated on a novel transdermal microprojection delivery system to produce a sterile product--adhesive compatibility.
Mahmoud Ameri, Xiaomei Wang, Yuh-Fun Maa. Journal of Pharmaceutical Science 99, 2123-34, 2010

Demonstrated Solid-State Stability of Parathyroid Hormone PTH(1–34) Coated on a Novel Transdermal Microprojection Delivery System. 
Mahmoud Ameri, Peter E. Daddona, Yuh-Fun Maa. Pharmaceutical Research 2454-2463, 2009

Effect of delivery parameters on immunization to ovalbumin following intracutaneous administration by a coated microneedle array patch system
Georg Widera, Juanita Johnson, Lomi Kim, Luz Libiran, Kofi Nyam, Peter E. Daddona, Michel Cormier. Vaccine 24, 1653-1664, 2006

Transdermal delivery of desmopressin using a coated microneedle array patch system
Michel Cormier, Bonny Johnson, Mamoud Ameri, Kofi Nyam, Luz Libiran, Dee Dee Zhang and Pete Daddona. Journal of Controlled Release, 97, 503-511, 2004

Transdermal delivery of Antisense Oligonucleotides
WeiQi Lin, Michel Cormier, and Peter E. Daddona. Celluar Drug Delivery: Principles and Practice, Humana Press, 227-285

Transdermal Drug Delivery
Brad Phipps, Michel Cormier, Bob Gale, Bill van Osdal, Jay Audett, Rama Padmanabhan and Peter Daddona. Encyclopedia of Biomaterials and Biomedical Engineering, Marcel Dekker, Inc. New York, 1677-1689, 2004

Macroflux® Transdermal Technology Development for the Delivery of Therapeutic Peptides & Proteins
Pete Daddona. PhD, Drug Delivery Technology 2, 54-57, 2002

Macroflux® Microprojection Array Patch Technology: A New and Efficient Approach for Intracutaneous Immunization
James A. Matriano, Michel Cormier, Juanita Johnson, Wendy A. Young, Margaret Buttery, Kofi Nyam, and Peter E. Daddona. Pharmaceutical Research, Vol 19, 63-70, 2002

Macroflux® Technology for Transdermal Delivery of Therapeutic Proteins and Vaccines
Michel Cormier and Peter E Daddona. Modified-Release Drug Delivery Technology, Marcel Dekker, Inc. New York, 589-598, 2002

Transdermal delivery of Antisense Oligonucleotides with Microprojection Patch (Macroflux®) Technology
WeiQi Lin, Michel Cormier, Amad Samiee, Angie Griffin, Bonny Johnson, Ching-Leou Teng, Gregory E. Hardee and Peter E. Daddona. Pharmaceutical Research, 19, 1789-1793, 2001